The raging lung inflammation that can contribute to death from the flu can be stopped in its tracks by a drug derived from a naturally occurring human protein, a new animal study suggests.
In mouse studies, all untreated animals given a lethal dose of influenza died within days. All but one of the infected mice treated with the experimental therapy not only survived, but remained energetic and kept weight on — despite having high levels of the flu virus in their lungs.
The experimental treatment is a heavy dose of MG53, part of a family of proteins that plays an essential role in cell membrane repair. Already identified as a potential therapy for conditions ranging from Alzheimer’s disease to persistent skin wounds, MG53 was found in this study to prevent death from a lethal flu infection by blocking excessive inflammation — without having any effect on the virus itself.
A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom. The team hopes to develop the molecules into new bacteria-killing drugs, an important advancement considering increasing numbers of antibiotic-resistant bacteria which can cause illness such as sepsis and tuberculosis.
In the study, published today in the Proceedings of the National Academy of Sciences, the researchers altered a highly toxic small protein from a common Asian wasp species, Vespula lewisii, the Korean yellow-jacket wasp. The alterations enhanced the molecule’s ability to kill bacterial cells while greatly reducing its ability to harm human cells. In animal models, the scientists showed that this family of new antimicrobial molecules made with these alterations could protect mice from otherwise lethal bacterial infections.
There is an urgent need for new drug treatments for bacterial infections, as
“For more than a decade, we’ve been building products to help people transform the way they work,” Google wrote in a blog post on Google Cloud. “Now, work itself is transforming in unprecedented ways. For many of us, work is no longer a physical place we go to, and interactions that used to take place in person are being rapidly digitized. Office workers no longer have impromptu discussions at the coffee machine or while walking to meetings together, and instead have turned their homes into workspaces. Frontline workers, from builders on a construction site to delivery specialists keeping critical supply chains moving, are turning to their phones to help get their jobs done. While doctors treating patients and local government agencies engaging with their communities are accelerating how they can use technology to deliver their services.”
Oct. 6 (UPI) — In a paper published Tuesday in the journal Nature Communications, scientists argue that rivalries among animal neighbors could drive cognitive evolution, encouraging the development of ‘Napoleonic’ intelligence.
To date, the study of cognitive evolution among animals has focused on antagonistic and co-operative social interactions within groups — the kinds of interactions thought to demand the development of so-called Machiavellian intelligence.
“Machiavellian intelligence is the House of Cards-style cunning that has evolved to get ahead in social politics within groups,” senior Andy Radford, professor of behavioral ecology at the University of Bristol in Britain, told UPI in an email.
Machiavellian intelligence and the related cognitive processes help animals compete and cooperate with their intergroup peers and relatives.
“We argue that animals also need ‘Napoleonic’ intelligence, the more Game of Thrones-style sharpness necessary to triumph in a world packed with rival outsiders,” Radford said.
High blood pressure: some people take medication to control it while others commit to low salt diets, exercise or yoga to reduce stress. Blood pressure is a primary vital sign, yet, remarkably, just how the body maintains it is still a mystery.
“We’ve been studying high blood pressure for 100 years and we still have the same ideas,” says Daniel Beard, Ph.D., the Carl J. Wiggers Collegiate Professor of Cardiovascular Physiology. In a new paper in JCI Insight, Beard, Feng Gu, Ph.D., from the department of molecular and integrative physiology, and their team describe a newly observed phenomenon in the way blood pressure is maintained in certain rats.
Their discovery comes on the heels of an inquiry into the linkage between stiffened arteries and high blood pressure, known clinically as hypertension. “What happens when you are hypertensive is your arteries get stiffer. But this is thought to be an
Study: Watching adorable animal videos has mental health benefits
The videos enhance one’s mood and provide relief against stress
After watching the videos, anxiety levels could drop as much as 50%
Watching images and videos of cute animals for a minimum of 30 minutes reduces stress and anxiety levels, according to a study conducted by researchers from the University of Leeds in the United Kingdom and the Tourism of Western Australia jointly.
In the study, first reported by CNN, the researchers monitored related vitals of 19 respondents comprised of 15 students and four university staff. To get the most ideal results, the study was conducted during the respondents’ winter exams as such a period proved to be the most stressful for both students and staff.
All participants had decreased blood pressure, heart rate, and anxiety levels after watching cute animal videos compiled for the session. Specifically, the participants
The MarketWatch News Department was not involved in the creation of this content.
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SHANGHAI, Sept. 18, 2020 /PRNewswire/ — As the world’s leading enterprise friendly blockchain platform, VeChain has officially joined the China Animal Health And Food Safety Alliance (hereafter referred as CAFA) as one of the council members. VeChain will be the sole public blockchain technology provider in the alliance, providing technical and infrastructural support for the council members.
CAFA is a government-backed organization directly under the Chinese National Agricultural Science Technology Innovation Alliance initiated by the Ministry of Agriculture of the People’s Republic of China, which aims to build a trustworthy platform that connects the government, industry associations, producer enterprises and research institutes in the food sector.
Since its launch, CAFA has revealed more than 130 members that are already signed up as official members of the alliance. These members consist of massive companies and bodies across upstream and downstream parties in the food industry, including supermarkets,