Immune T cells swarm to tumours by following a chemical gradient left by other cancer-killing T cells — ScienceDaily

When immune system T cells find and recognise a target, they release chemicals to attract more T cells which then swarm to help subdue the threat, shows a new study published today in eLife.

The discovery of this swarming behaviour, and the chemical attractants that immune cells use to direct swarms towards tumours, could one day help scientists develop new cancer therapies that boost the immune system. This is particularly important for solid tumours, which so far have been less responsive to current immunotherapies than cancers affecting blood cells.

“Scientists have previously thought that cancer-killing T cells identified tumours by randomly searching for them or by following the chemical trails laid by other intermediary immune cells,” says lead author Jorge Luis Galeano Niño, a PhD graduate at UNSW Sydney. “We wanted to investigate this further to see if it’s true, or whether T cells locate tumours via another mechanism.”

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Huawei’s Rivals Are Already Filling A $27 Billion Hole Left By US Sanctions

After more US sanctions have all-but-crippled the future of Huawei’s global networks business — and its efforts to become the dominant 5G provider — dollar signs are already materializing for its rivals.

At the crux of Huawei’s withdrawal is an annual $27 billion opportunity for its competitors — including Nokia, Ericsson and Samsung — to become the go-to providers of 5G and other telecommunication services to domestic carriers, says Ryan Koontz, an analyst at Rosenblatt Securities. “It’s a massive economic transition,” says Koontz. “It’s relatively urgent for these carriers to make the change.” 

The multi-billion dollar market opportunity, which hinges on Huawei’s sales figures for the year ended September, will not evaporate overnight, Koontz says, but will likely be absorbed over the next three to four years. 

Because

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Apple’s New 5G IPhones May Be Left on the Shelf

(Bloomberg Opinion) — Apple Inc. has been in the spotlight lately, between antitrust scrutiny of its mobile operating system and the legal battle it’s waging with Fortnite-maker Epic Games Inc. over its App Store. Those developments pale, however, in comparison to the company’s main event next week: the unveiling of its latest iPhones.

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For all the talk about Apple’s shift to services and subscriptions, the tech giant’s business is still dependent on its core hardware products, so Tuesday’s presentation will be a must-see for investors. There could be a problem this year, though. The lineup’s most vaunted feature — fifth-generation wireless capability — may not be ready for prime time. 

The Cupertino, California-based company is expected to unveil four new iPhone models with 5G capabilities as well as a different physical design and a wider choice of screen sizes, Bloomberg News reported last month. Apple is already touting 

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T-Mobile Expands Home Internet to More Than 450 Cities & Towns Left High-and-Dry by AT&T

No contract, $50 per month high-speed Internet access is rolling out to vast swaths of the country, including rural America, for both T-Mobile and non-T-Mobile customers alike

What’s the news: T-Mobile is throwing a lifeline to many communities being abandoned by AT&T. It’s expanding its $50 / month, no two-year contract Home Internet service into more than 450 cities and towns that AT&T is deserting. The Un-carrier is also opening the service to non-T-Mobile customers in these new areas.

Why it matters: Many parts of the country have extremely limited, slow Internet options and the pandemic has increased our reliance on Internet connectivity. AT&T dropping DSL service in those communities makes an already difficult situation that much worse.

Who it’s for: 20 million households in thousands of locations that are sick-and-tired of their Internet access provider jerking them around.

What AT&T takes away, T-Mobile brings back. Following news that AT&T

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Valve’s Last Stand Update Could Be Hinting About ‘Left 4 Dead 3’

KEY POINTS

  • Valve recently released The Last Stand DLC for “Left 4 Dead 2
  • The new campaign introduced new weapons, rolled out bug fixes and featured characters
  • The Last Stand DLC could indicate that Valve is open to developing “Left 4 Dead 3”

Valve rolled out The Last Stand DLC campaign for “Left 4 Dead 2,” ending an almost a decade of update drought for the successful horror title, but a new report believes that the studio’s recent activities could be hinting that “Left 4 Dead 3” could be on the way.

Gamerant speculated that Valve’s recent push towards the new content of “Left 4 Dead” and “Half-Life” could indicate that a sequel of the horror title could finally be on the way. While many believed that Valve is no longer actively developing games, the release of “Half-Life: Alyx” and The Last Stand update prove otherwise.

The publication also thinks

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How Blue and White is both Left and Right

The party formed to represent the Israeli center has been going to extremes.On one side there are the loud voices from the Left side of the party, but there are voices on the Center-Right side as well.On the Center-Left, there is Tourism Minister Asaf Zamir, whose resignation takes effect on Monday; Science and Technology Minister Izhar Shay, who almost quit last week; and MKs Miki Haimovich and Ram Shefa, who voted against limits on political demonstrations in the Knesset.Haimovich made news on Sunday, when she said there is a group that is growing in Blue and White that is interested in breaking up the partnership with Likud. Other MKs talked about starting to vote more independently.But even if they are growing, they are still the minority in the party. The overwhelming majority of the MKs in the Blue and White-Derech Eretz-Labor bloc prefers staying the course and continuing the strategy
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Indian start-up ShareChat is one of many looking to fill the vacuum left by TikTok ban

  • ShareChat, a Twitter-backed Indian social media platform that caters to users in 15 regional languages, launched a short-video sharing app just days after New Delhi banned TikTok.
  • The app, Moj, now has more than 80 million monthly active users who spend on average 34 minutes on the platform, the company said. 
  • The TikTok ban left a vacuum that local start-ups are moving in to fill. 



a close up of a person wearing a mask: A girl wearing a protective mask depicting the TikTok logo poses for a picture in Mumbai, India, July 1, 2020.


© Provided by CNBC
A girl wearing a protective mask depicting the TikTok logo poses for a picture in Mumbai, India, July 1, 2020.

SINGAPORE — India’s ban of the popular short-video sharing app TikTok has left a vacuum that local start-ups are moving in to fill. 

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One of those start-ups is ShareChat, a Twitter-backed Indian social media platform that caters to users in 15 regional languages.

Citing national security concerns, New Delhi announced the ban on TikTok, which is owned by Beijing-based

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After 40 Years, Updated Pain Definition Aims To Include Those Once Left Out

It’s not uncommon for people with chronic pain but no clear injury to deal with doubting physicians.

Katie Clark, a retired middle school English Language Arts teacher in Michigan with fibromyalgia, said she has been lucky with her doctors. Fibromyalgia causes chronic pain that doctors think arises from amplified pain signals in the brain and spinal cord.

“I’ve been fortunate to have doctors that mostly believe the pain I feel is real,” she said. But even then, “They don’t fully understand that it affects you emotionally, physically, your energy level, your ability to think straight. That is difficult to communicate to doctors.”

In the past, healthcare providers have ascribed to a narrow definition of pain, viewing

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Left 4 Dead 2 Gets Huge ‘Last Stand’ Update, But Mac Version Remains 32-Bit

After almost a decade since the game’s release on Mac, Valve’s iconic co-op zombie shooter “Left 4 Dead 2” has just got a huge update thanks to new content pack “The Last Stand.”

It has been many years since the infection first hit. Radio silence, no sign of life, nothing but lingering hopes… CEDA is not going to save us. But there is hope! A few brave souls have continued the fight against all odds, and soon we can all benefit from their resilience.

Created by the L4D2 community and officially endorsed by Valve, the update includes over 1,000 changes to the game, including 26 new survival maps, new weapons, new enemy types, new animations, and unused dialogue. There are also several new achievements, many bug fixes and a handful of user interface enhancements to make the game feel fresh again.

The only downside to today’s development for old-school gaming

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